Publications
Publications by Paul B. Savage.
92. Savage, P. B.; Bendelac, A.; Teyton, L. Chem. Soc. Rev. 2006, 35, 771-779. Glycolipids for natural killer T cells.
91. Sagiv, Y.; Hudspeth, K.; Mattner, J.; Schrantz, N.; Stern, R. K.; Zhou, D.; Savage, P. B.; Teyton, L.; Bendelac, A. J. Immunol. 2006, 177, 26-30. Cutting edge: Impaired glycosphingolipids trafficking and NKT cell development in mice lacking Niemann-Pick Type C1 protein.
90. Campos-Martín, Y.; Colmenares, M.; Gozalbo-López, B.; López-Núñez, M.; Savage, P. B.; Martínez-Naves, E. J. Immunol. 2006, 176, 6172-6179. Immature human dendritic cells infected with Lieshmania infantum are resistant to NK-mediated cytolysis but are efficiently recognized by NKT cells.
89. Wei, D. G.; Curran, S. A.; Savage, P. B.; Teyton, L.; Bendelac, A. J. Exp. Med. 2006, 203, 1197-1207. Mechanisms imposing the V-beta bias of V-alpha-14 NKT cells and consequences for microbial glycolipid recognition.
88. Meyer, E. H.; Goya, S.; Akbari, Ol.; Berry, G. J.; Savage, P. B.; Kronenberg, M.; Nakayama, T.; DeKruyff, R. H.; Umetsu, D. T. Proc. Natl Acad. Sci. 2006, 103, 2782-2787. Glycolipid mediated activation of iNKT cells is sufficient to induce airway hyperreactivity indpendent of conventional CD4+ T cells.
87. Liu, Y.; Goff, R. D.; Zhou, D.; Mattner, J.; Sullivan, B. A.; Khurana, A.; Cantu, C. III, Altman, J. D.; Teyton, L.; Bendelac, A.; Savage, P. B. J. Immun. Methods 2006, 312, 34-39. A modified a-galactosyl ceramide for staining and stimulating natural killer T cells.
86. Farruggia, G.; Iotti, S.; Prodi, L.; Montalti, M.; Zaccheroni, N.; Savage, P. B.; Trapani, V.; Sale, P.; Wolf, F. I. J. Am. Chem. Soc. 2006, 127, 344-350. 8-Hydroxyquinoline derivatives as fluorescent sensors for magnesium in living cells.
85. Kichler, A.; Leborgne, C.; Savage, P. B.; Danos, O. J. Controlled Release 2005, 107, 174-182. Cationic steroid antibiotics demonstrate DNA delivery properties.
84. Farruggia, G.; Iotti, S.; Prodi, L.; Montalti, M.; Zaccheroni, N.; Savage, P. B.; Trapani, V.; Sale, P.; Wolf, F. I. J. Am. Chem. Soc. in press. 8-Hydroxyquinoline derivatives as fluorescent sensors for magnesium in living cells.
83. Zajonc, D. M.; Cantu, C. III; Mattner, J.; Zhou, D.; Savage, P. B.; Bendelac, A.; Wilson, I A.; Teyton, L. Nature Immunology 2005, 6, 810-818. Structure and function of a potent α-galactosylceramide agonist for the semi-invariant NKT cell receptor.
82. Liu, Y.; Govv, R. D.; Zhou, D.; Mattner, J.; Sullivan, B. A.; Khurana, A.; Cantu, C. III, Altman, J. D.; Teyton, L.; Bendelac, A.; Savage, P. B., submitted (J. Immun. Methods). A modified α-galactosyl ceramide for natural killer T cell staining with CD1d tetramers.
81. Mattner, J.; DeBord, K. L.; Goff, R. D.; Cantu, C.; Zhou, D.; Saint-Mezard, P.; Wang, V.; Gao, Y.; Yin, N.; Hoebe, K.; Schneewind, O.; Ismail, N.; Walker, D.; Buetler, B.; Teyton, L.; Savage, P. B.; Bendelac, A. Nature 2005, 434, 525-528. Both exogenous and endogenous glycolipid antigens activate NKT cells during microbial infections.
80. Bronson, R. T.; Michaelis, D. J.; Lamb, R. D.; Husseini, G. A.; Farnsworth, P. B.; Linford, M. A.; Izatt, R. M; Bradshaw, J. S.; Savage, P. B. Org. Lett. 2005, 7, 1105-1108. Efficient immobilization of a cadmium chemosensor in a thin film: generation of a cadmium sensor prototype.
79. Zhou, D.; Mattner, J.; Cantu, C.; Schrantz, N.; Yin, N.; Gao, Y.; Sagiv, Y.; Hudspeth, K.; Wu, Y.; Yamashita, T.; Teneberg, S.; Wang, D.; Proia, R.; Levery, S. B.; Savage, P. B.; Teyton, L.; Bendelac, A. Science 2004, 306, 1786-1789. Lysomal glycosphingolipid recognition by NKT cells.
78. Ding, B.; Taotafa, U.; Orsak, T.; Chadwell, M. Org. Lett. 2004, 6, 3433-3436. Synthesis and characterization of peptide-cationic steroid antibiotic conjugates.
77. Savage, P. B.; Li, C. “Steroid Derived Antibiotics,” US patent # 6,767,904, July 27, 2004.
76. Ding, B.; Yin, N.; Liu, Y.; Cardenas-Garcia, J.; Evanson, R.; Orsak, R.; Fan, M.; Turin, G.; Savage, P. B. J. Am. Chem. Soc. 2004, 126, 13642-13648. Origins of cell selectivity of cationic steroid antibiotics.
75. Goff, R. D.; Gao, Y.; Mattner, J.; Zhou, D.; Yin, N.; Cantu, C. III; Teyton, L.; Bendelac, A.; Savage, P. B. J. Am. Chem. Soc. 2004, 126, 13602-13603. Effects of lipid chain lengths in a-galactosylceramides on cytokine release by natural killer T cells.
74. Bronson, R. T.; Montalti, M.; Prodi, L.; Zaccheroni, N.; Lamb, R. D.; Dalley, N. K.; Izatt, R. M.; Bradshaw, J. S.; Savage, P. B. Tetrahedron 2004, 60, 11139-11144. Origins of “on-off” fluorescent behavior of 8-hydroxyquinoline-containing chemosensors.
73. Zhou, D.; Cantu, C. C.; Sagiv, Y.; Kulkarni, A. B.; Qi, X.; Morales, C.; Grabowski, G. A.; Benlagha, K.; Savage, P. B.; Bendelac, A. Teyton, L. Science 2004, 303, 523-527. Editing of Cd1-bound lipid antigens by endosomal lipid transfer proteins.
72. Xue, G.; Bradshaw, J. S.; Dalley, N. K.; Savage, P. B.; Izatt, R. M. J. Heterocyclic Chem. 2003, 40, 383-388. Synthesis of trans-disubstituted cyclam ligands appended with two 6-hydroxymethylpyridin-2-ylmethyl sidearms: crystal structures of the 1,8-dimethyl-4,11-di(6-hydroxymethylpyridin-2-ylmethyl)cylam ligand and its Co(II) and Ni(II) complexes.
71. Hook, G. L.; Kimm, G.; Betsinger, G.; Savage, P. B.; Swift, A.; Logan, T.; Smith, P. A. J. Sep. Sci. 2003, 26, 1091-1096. Solid phase microextraction sampling and gas chromatography/mass spectrometry for filed detection of the chemical warfare agent O-ethyl-S-(s-diisopropylaminoethyl)methylphosphonothiolate (VX).
70. Song, H.-C.; Chen. Y.W.; Yao, J.-H.; Bradshaw, J. S.; Savage, P. B.; Izatt, R. M. J. Heterocyclic Chem. 2003, 40, 475-479. Synthesis of diazadithiacrown ethers containing appended coumarin or 1-aminonaphthalene sidearms.
69. Hook, G. L.; Kimm, G.; Koch, D.; Savage, P. B.; Ding, B.; Smith, P. A. J. Chrom. A 2003, 992, 1-9. Detection of VX contamination in soil through solid-phase microextraction sampling and gas chromatography–mass spectrometry of the VX degradation product bis(diisopropylaminoethyl)disulfide.
68. Cantu, C.; Benlagha, K.; Savage, P. B.; Bendelac, A.; Teyton, L. J. Immunol. 2003, 170, 4673-4682. The paradox of immune molecular recognition of a-galactosylceramide: low affinity, low specificity for CD1d, high affinity for ab T cell receptors.
67. Yin, N.; Marshall, R. L.; Matheson, S.; Savage, P. B. J. Am. Chem. Soc. 2003, 126, 2426-2435. Synthesis of lipid A derivatives and their interactions with polymyxin B and polymyxin B nonapeptide.
66. Kawakami, J.; Bronson, R. T.; Xue, G.; Bradshaw, J. S.; Izatt, R. M.; Savage, P. B. Supramol. Chem. 2003, 1, 221-227. Characterization of bis-8-hydroxyquinoline-armed diazatrithia-16-crown-5 and diazadibenzo-18-crown-6 ligands as fluorescent chemosensor for zinc.
65. Savage, P. B.; Li, C.; Taotafa, U.; Ding, B.; Guan, Q. FEMS Lett. 2002, 217, 1-7. Antibacterial properties of cationic steroid antibiotics.
64. Zhou, X. T.; Forestier, C.; Goff, R. D.; Li, C.; Teyton, L.; Bendelac, A.; Savage, P. B. Org. Lett. 2002, 4, 1267-1270. Synthesis and NKT cell stimulating properties of fluorophore and biotin appended 6”-amino-6”-deoxy-galactosylceramides.
63. Posner, R. G.; Savage, P. B.; Peters, A. S.; Macias, A.; DelGado, J.; Schwarz, G.; Sklar, L. A.; Hlavacek, W.; Goldstein, B. Molecular Immunology 2002, 38, 1221-1228. A quantitative approach for studying IgE-FceRI aggregation.
62. Chiu, Y.-H.; Park, S.-H.; Benlagha, K.; Forestier, C.; Jayawardena-Wolf, J.; Savage, P. B.; Teyton, L.; Bendelac, A. Nature Immunol. 2002, 3, 55-60. Multiple defects of antigen presentation and T cell development in mice expressing tail-truncated CD1d.
61. Kluchinsky, T. A. Jr.; Savage, P. B.; Fitz, R.; Smith, P. A. AIHA Journal 2002, 63, 493-496. Liberation of hydrogen cyanide and hydrogen chloride during high temperature dispersion of CS riot control agent.
60. Ding, B.; Guan, Q.; Walsh, J. P.; Boswell, J. S.; Winter, T. W.; Winter, E. S.; Boyd, S. S.; Li, C.; Savage, P. B. J. Med. Chem. 2002, 45, 663-669. Correlation of the antibacterial activities of cationic peptide antibiotics and cationic steroid antibiotics.
59. Savage, P. B. Curr. Med. Chem. 2002, 3, 293-304. Cationic steroid antibiotics.
58. Savage, P. B. European J. Org. Chem. 2002, 759-768. Design, synthesis and characterization of cationic peptide and steroid antibiotics.
57. Xue, G.-P.; Bradshaw, J. S.; Dalley, N. K.; Savage, P. B.; Izatt, R. M.; Prodi, L.; Montalti, M.; Zaccheroni, N. Tetrahedron 2002, 58, 4809-4815. Synthesis of azacrown ethers with quinoline-based sidearms as potential zinc(II) fluorophores.
56. Song, H.-C.; Bradshaw, J. S.; Y.-W. Chen, Xue, G.-P.; Li, W.-M.; Krakowiak, K. E.; Savage, P. B.; Xu, Z.-L.; Izatt, R. M. Supramolecular Chem. 2002, 14, 263-269. Synthesis of new crown ethers containing appended pyridine, 10-hydroxybenzoquinoline, 8-hydroxyquinoline and 2-amino-1-hydroxybiphenyl sidearms.
55. Kluchinshy, T. A.; Sheely, M. V.; Savage, P. B.; Smith, P. A. J. Chromatography A 2002, 952, 205-213. Formation of 2-chlorobenzylidenemalononitrile (CS riot control agent) thermal degradation products at elevated temperatures.
54. Smith, P. A.; Kluchinsky, T. A.; Savage, P. B.; Erickson, R. P.; Lee, A. P.; Williams, K.; Stevens, M.; Thomas, R. J. AIHA J. 2002, 63, 284-292. Traditional sampling with laboratory analysis and solid phase microextraction sampling with field gas chromatography/mass spectrometry by military industrial hygienists.
53. Savage, P. B.; Li, C. “Steroid Derived Antibiotics,” US patent # 6,486,148, November 26, 2002.
52. Savage, P. B.; Li, C. “Steroid Derived Antibiotics,” US patent # 6,350,738, February 26, 2002.
51. Song, H. C.; Chen, Y.-W.; Song, J.-C.; Savage, P. B.; Xue, G.-P.; Chiara, J. A.; Krakowiak, K. E.; Izatt, R. M.; Bradshaw, J. S. J. Heterocyclic Chem. 2001, 38, 1369-1376. New diazadi(and tri)thia-21-crown-7 ethers containing 8-hydroxyquinoline side arms.
50. Xue, G.-P.; Bradshaw, J. S.; Dalley, N. K.; Savage, P. B.; Krakowiak, K. E.; Izatt, R. M.; Prodi, L.; Montalti, M.; Zaccheroni, N. Tetrahedron 2001, 57, 7623-7628. Convenient synthesis and preliminary photophysical properties of novel 8-aminoquinoline appended diaza-18-crown-6 ligands.
49. Xue, G.-P.; Savage, P. B.; Krakowiak, K. E.; Izatt, R. M.; Bradshaw, J. S. J. Heterocyclic Chem. 2001, 38, 1453-1457. Synthesis of diazadibenzo-18-crown-6 ligands with appended chromophoric and fluorophoric groups as potential metal ion chemosensors.
48. Song, H. C.; Bradshaw, J. S.; Chen, Y.-W.; Xue, G.-P.; Chiara, J. A.; Krakowiak, K. E.; Savage, P. B.; Xue, Z.-L.; Izatt, R. M. ARKIVOK 2001, 2, ms#116. Syntheses of diazadithiacrown ethers containing two 8-hydroxyquinoline side arms.
47. Kluchinsky, T. A., Jr.; Savage, P. B.; Sheely, M. V.; Thomas R. J.; Smith, P. A. Microcolumn Sep. 2001, 13, 186-190. Identification of CS-derived compounds formed during heat-dispersion of CS riot control agent.
46. Bradshaw, J. S.: Song, H.-C.; Xue, G.-P.; Bronson, R. T.; Chiara, J. A.; Krakowiak, K. E.; Savage, P. B.; Izatt, R. M. Supramol. Chem. 2001, 13, 499-505. Synthesis of diazadi(and tri)thiacrown ethers containing two 5-substituent(or 2-methyl)-8-hydroxyquinoline side arms.
45. Savage, P. B. Annals of Med. 2001, 33, 167-171. Multidrug resistant bacteria: overcoming antibiotic permeability barriers of gram-negative bacteria.
44. Lee, S. C.; Izatt, R. M.; Zhang, X. X.; Nelsen, E. G.; Lamb, J. D.; Savage, P. B.; Bradshaw, J. S. Inorg. Chim. Acta 2001, 317, 174-180. Highly selective copper(II) ion receptors: tetraazacrown ethers bearing two 8-hydroxyquinoline side arms.
43. Bronson, R. T.; Bradshaw, J. S.; Savage, P. B.; Fuangwasdi, S.; Lee, S. C.; Krakowiak, K. E.; Izatt, R. M. J. Org. Chem. 2001, 66, 4752-4758. Bis-8-hydroxyquinoline-armed diazatrithia-15-crown-5 and diazathithia-16-crown-5 ligands: possible fluorophoric metal ion sensors.
42. Prodi, L.; Montalti, M.; Zaccheroni, N.; Bradshaw, J. S.; Izatt, R. M.; Savage, P. B. J. Incl. Phenom. 2001, 41, 123-127. pH dependence of the luminescent properties of metal ion complexes of 5-chloro-8-hydroxyquinoline appended diaza-18-crown-6.
41. Schmidt, E. J.; Boswell, S. R.; Walsh, J. P.; Schellenberg, M. M.; Winter, T. W.; Li, C.; Allman, G. W.; Savage, P. B. J. Antimicrob. Chemother. 2001, 47, 671-674. Activities of cholic acid-derived antimicrobial agents against multidrug-resistant bacteria.
40. Prodi, L.; Montalti, M; Zaccheroni, N; Bradshaw, J. S.; Izatt, R. M.; Savage, P. B. Tetrahedron Lett. 2001, 42, 2941-2944. Characterization of 5-methoxyquinoline appended diaza-18-crown-6 as a chemosensor for cadmium.
39. Dalley, N. K.; Xue, G.-P.; Bradshaw, J. S.; Zhang, X. X.; Harrison, R. G.; Savage, P. B.; Krakowiak, K. E.; Izatt, R. M. J. Heterocyclic Chem. 2001, 38, 1-9. A new diaza-18-crown-6 ligand containing two quinolin-8-ylmethyl side arms: crystal structures and characterization of the ligand, the protonated ligand and its mononuclear barium (II) and dinuclear copper (II) complexes.
38. Xue, G.-P.; Bradshaw, J. S.; Song, H.-C.; Bronson, R. T.; Savage, P. B.; Krakowiak, K. E.; Izatt, R. M.; Prodi, L.; Montalti, M.; Zaccheroni, N. Tetrahedron 2001, 57, 87-91. A convenient synthesis and preliminary photophysical study of novel fluoroionophores: macrocyclic polyamines containing two dansylamidoethyl side arms.
37. Zhou, X.-T.; Rehman, A.; Li, C.; Savage, P. B. Org. Lett. 2000, 2, 3015-3018. Preparation of a protected triamino-analogue of cholic acid and sequential incorporation of amino acids in solution and on a solid support.
36. Taotafa, U.; McMullin, D. M.; Lee, S. C.; Savage, P. B. Org. Lett. 2000, 2, 4117-4120. Anionic facial amphiphiles from cholic acid.
35. Guan, Q.; Schmidt, E. J.; Boswell, S. R.; Li, C.; Allman, G. W.; Savage, P. B. Org. Lett. 2000, 2, 2837-2840. Preparation and characterization of cholic acid-derived antimicrobial agents with controlled stabilities.
34. Prodi, L.; Bargossi, C.; Montalti, M.; Zaccheroni, N.; Su, N.; Bradshaw, J. S.; Izatt, R. M.; Savage, P. B. J. Am. Chem. Soc. 2000, 122, 6769-6770. An effective fluorescent chemosensor for mercury ions.
33. Savage, P. B.; Li, C. Exp. Op. Invest. Drugs 2000, 9, 263-269. Cholic acid derivatives: novel antimicrobials.
32. Xue, G.-P.; Bradshaw, J. S.; Su, N.; Krakowiak, K. E.; Savage, P. B.; Izatt, R. M. J. Heterocyclic Chem. 2000, 37, 1-9. Syntheses of two 1,3-2,4-calix[4]bis-crown ethers containing two 1,2-phenylene and one pyridine or anisole units in each crown ether moiety.
31. Su, N.; Bradshaw, J. S.; Xue, G.; Dalley, N. K.; Zhang, X. X.; Savage, P. B.; Krakowiak, K. E.; Izatt, R. M. J. Heterocyclic Chem. 2000, 37, 711-720. Synthesis, crystal structures, and metal ion complexation studies of novel diaza-18-crown-6 ligands containing aromatic thiol-derived side arms.
30. Fleming, S. A.; Hart, G. R.; Savage, P. B. J. Chem. Ed. 2000, 77, 790-794. Molecular orbital animations for organic chemistry.
29. Xue, G.-P.; Bradshaw, J. S.; Chiara, J. A.; Savage, P. B.; Krakowiak, K. E.; Izatt, R. M. Syn. Lett. 2000, 1181-1183. “A convenient synthesis of novel fluorophores: macrocyclic polyamines containing two dansylamidoethyl side arms.
28. Xue, G.-P.; Savage, P. B.; Bradshaw, J. S.; Zhang, X. X.; Izatt, R. M. in Advances in Supramolecular Chemistry, Vol. 7; JAI Press, 2000, pp. 99-137. Functionalized macrocyclic ligands as sensory molecules for metal ions.
27. Bradshaw, J. S.; Izatt, R. M.; Savage, P. B.; Bruening, R. L.; Krakowiak, K. E. Supramolecular Chem. 2000, 12, 23-38. The design of ion selective macrocycles and the solid-phase extraction of ions using molecular recognition technology: A synopsis.
26. Li, C.; Lewis, M. R.; Gilbert, A. B.; Noel, M. D.; Scoville, D. H.; Allman, G. W.; Savage, P. B. Antimicrob. Agents. Chemother. 1999, 43, 1347-1351. Antimicrobial activities of amine- and guanidine-functionalized cholic acid derivatives.
25. Li, C.; Budge, L. P.; Driscoll, C. D.; Willardson, B. M.; Allman, G. W.; Savage, P. B. J. Am. Chem. Soc. 1999, 121, 931-940. Incremental conversion of outer-membrane permeabilizers into potent antibiotics for Gram-negative bacteria.
24. Rehman, A.; Li, C.; Budge, L. P.; Street, S. E.; Savage, P. B. Tetrahedron Lett. 1999, 40, 1865-1868. Preparation of amino acid-appended cholic acid derivatives as sensitizers of Gram-negative bacteria.
23. Li, C.; Rehman, A.; Dalley, N. K.; Savage, P. B. Tetrahedron Lett. 1999, 40, 1861-1864. Short syntheses of triamine-derivatives of cholic acid.
22. Su, N.; Bradshaw, J. S.; Zhang, X. X.; Song, H.-C.; Savage, P. B.; Xue, G.-P.; Krakowiak, K. E.; Izatt, R. M. J. Org. Chem. 1999, 64, 8855-8865. Syntheses and metal ion complexation of novel 8-hydroxyquinoline-containing diaza-18-crown-6 ligands and analogs.
21. Su, N.; Bradshaw, J. S.; Savage, P. B.; Krakowiak, K. E.; Izatt, R. M.; DeWall, S. L.; Gokel G. W. Tetrahedron 1999, 55, 9737-9746. Syntheses and aggregate study of bisphenol-containing diaza-18-crown-6 ligands.
20. Su, N.; Bradshaw, J. S.; Savage, P. B.; Krakowiak, K. E.; Izatt, R. M. J. Org. Chem. 1999, 64, 3825-3836. Diaza-18-crown-6 ligands containing two aminophenol sidearms: new heterobinuclear metal ion receptors.
19. Yang, Z.; Bradshaw, J. S.; Zhang, X. X.; Savage, P. B.; Krakowiak, K. E.; Dalley, N. K.; Su, N.; Bronson, T.; Izatt, R. M. J. Org. Chem. 1999, 64, 3162-3172. New yetraazacrown ethers containing two pyridine, quinoline, 8-hydroxyquinoline or 8-aminoquinoline sidearms.
18. Su, N.; Bradshaw, J. S.; Savage, P. B.; Krakowiak, K. E.; Izatt, R. M. J. Heterocyclic Chem. 1999, 36, 771-780. Syntheses of diaza-18-crown-6 ligands containing two 4-hydroxyazobenzene, two benzimidazole, two uracil, two anthraquinone, or two ferrocene units.
17. Fleming S. A.; Hart, G. R.; Savage, P. B. Organic Reaction Animations v1.5; W. W. Norton: New York, 1999. (Fleming S. A.; Hart, G. R.; Savage, P. B. Organic Reaction Animations v1.0; W. W. Norton: New York, 1998.)
16. Li, C.; Peters, A. S.; Meredith, E. L.; Allman, G. H.; Savage, P. B. J. Am. Chem. Soc. 1998, 120, 2961-2962. Design and synthesis of potent sensitizers of Gram-negative bacteria based on a cholic acid scaffolding.
15. Prodi, L.; Bolletta, F.; Montalti, M.; Zaccheroni, N.; Savage, P. B.; Bradshaw, J. S.; Izatt, R. M. Tetrahedron Lett. 1998, 39, 5451-5454. A fluorescent sensor for magnesium ions.
14. Marshall, R. L.; Dalley, N. K.; Savage, P. B. Tetrahedron Lett. 1998, 39, 3923-3926. Synthesis of novel 3’,6’-dideoxy-3’,6’-epithio and 2’,6’-dideoxy-2’,6’-epithio nucleosides.
13. Smith, P. A.; Bowerbank, C. R.; Savage, P. B.; Drown, D. B.; Lee, M. L.; Alexander, W.; Jederberg, W. W.; Still, K. Appl. Occ. Env. Hygiene 1998, 14, 171-179. Conjugation of 7-oxodehydroabietic acid to lysine, a haptenation mechanism for an oxidized resin acid with dermal sensitizing properties.
12. Bordunov, A. V.; Bradshaw, J. S.; Bastushok, V. N.; Zhang, X. X.; Kou, X.; Dalley, N. K.; Yang, Z.; Savage, P. B.; Izatt, R. M. Tetrahedron 1997, 53, 17595-17603. Azacrown ethers containing oximic and Schiff base sidearms-potential heteronuclear metal ion receptors.
11. Savage, P. B.; Thomas, W. D.; Dalley, N. K. J. Incl. Phenom. 1997, 29, 335-339. Synthesis of two new glycophanes comprised of thioglucose molecules linked by hydrocarbons.
10. Homlgren, S. K.; Savage, P. B.; Desper, J. M.; Schladetzky, K. D.; Powell, D. R.; Gellman, S. H. Tetrahedron, 1997, 53, 12249-12257. Steric control of oxidation selectivity in macrocyclic phosphine oxide-dithioethers
9. Paquette, L. A.; Sun, L.-Q.; Friedrich, D.; Savage, P. B. J. Am. Chem. Soc. 1997, 119, 8438-8439. Total synthesis of (+)-epoxydictymene. Application of alkoxy-directed cyclization to diterpenoid construction.
8. Paquette, L. A.; Sun, L.-Q.; Friedrich, D.; Savage, P. B. Tetrahedron Lett. 1997, 38, 195-199. Highly enantioselective total synthesis of natural epoxydictymene. An alkoxy-directed cyclization route to highly strained trans-oxabicyclo[3.3.0]octanes.
7. Savage, P. B.; Holmgren, S. K.; Gellman, S. H. J. Am. Chem. Soc. 1994, 116, 4069-4070. Anion and ion Pair complexation by a macrocyclic phosphine oxide disulfoxide.
6. Savage, P. B.; Gellman, S. H. J. Am. Chem. Soc. 1993, 115, 10448-10449. Complexation of ammonium hexoses: evidence for contributions from OH-OH hydrogen bonds in a hydroxylic medium.
5. Savage, P. B.; Holmgren, S. K.; Gellman, S. H. J. Am. Chem Soc. 1993, 115, 7900-7901. Optimization of a phosphine oxide-disulfoxide array for multipoint hydrogen bonding to ammonium ions.
4. Savage, P. B.; Holmgren, S. K.; Desper, J. M.; Gellman, S. H. Pure Appl. Chem. 1993, 65, 461-468. Macrocycles containing sulfur and phosphorus: structure and complexation properties.
3. Savage, P. B.; Desper, J. M.; Gellman, S. H. Tetrahedron Lett. 1992, 33, 2107-2110. Stereoselective oxidation of an eleven-membered heterocycle.
2. McDaniel, C. W.; Bradshaw, J. S.; Krakowiak, K. E.; Izatt, R. M.; Savage, P. B.; Tarbet, B. J.; Bruening, R. L. J. Heterocyclic Chem. 1989, 26, 413-419. Preparation of crown compounds containing allyloxymethyl or butenyl groups for attachment to silica gel or containing long chain lipophilic groups for use in liquid membrane systems.
1. Bradshaw, J. S.; Krakowiak, K. E.; Bruening, R. L.; Tarbet, B. J.; Savage, P. B.; Izatt, R. M. J. Org. Chem. 1988, 53, 3190-3197. Synthesis of (allyloxy)methyl-substituted diaza-18-crown-6 compounds for attachment to silica gel.

